Differential Metabolites Clustering Analysis Service

To assess the appropriateness of candidate metabolites and to more comprehensively and intuitively display the relationships among samples and the differential expression patterns of metabolites across different samples, hierarchical clustering is utilized based on the expression levels of significantly differential metabolites. This approach aids in accurately identifying marker metabolites and examining changes in associated metabolic processes. Generally, when the selected candidate metabolites are appropriate and accurate, samples from the same group tend to cluster together. Additionally, metabolites within the same cluster exhibit similar expression patterns and may participate in closely related metabolic pathway. The figure below illustrates the hierarchical clustering results of significant differential metabolites.

Figure 1. Hierarchical Clustering Results of Significant Differential Metabolites