ATP Metabolism-Related Substances Analysis Service

ATP metabolism involves several key small molecules, including adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP), oxidized nicotinamide adenine dinucleotide (NAD+), reduced nicotinamide adenine dinucleotide (NADH), coenzyme A (CoA), acetyl coenzyme A (acetyl-CoA), and inorganic phosphate (Pi). ATP is the primary unit of energy transfer within cells, crucial for storing and transmitting chemical energy.

 

MtoZ Biolabs has developed a platform for detecting ATP metabolism-related small molecules, utilizing the ACQUITY UPLC/TripleQuad5500 system (Waters/AB Sciex). This platform allows for both quantitative and qualitative analysis, with 95% of the substances being quantified using standards and isotope-labeled standards.

 

Services at MtoZ Biolabs

Figure 1. Detectable ATP Metabolism-Related Small Molecules

 

Sample Submission Requirements

1. Types of Samples

Serum, plasma, urine, bile, bile acids; cells, liver, brain tissue and other animal tissues, as well as feces; plants, yeast, microorganisms, etc.

 

2. Sample Quantities

(1) Blood, bile samples, etc.: 10 µL

(2) Various tissues: 10 mg

(3) Feces, etc.: 10 mg

For other sample types and quantities, please contact MtoZ Biolabs sales.

 

3. Sample Transportation

Considering that 3-4 kg of dry ice will evaporate in one day, ensure to use an adequate amount of dry ice (preferably larger blocks as they evaporate slower) and seal the samples in a foam box. Opt for the fastest shipping method possible to minimize sample degradation during transit.

 

Deliverables

MtoZ Biolabs will provide a comprehensive technical report, including:

1. Experimental Procedures

2. Relevant Mass Spectrometry Parameters

3. Quantitative or Qualitative Data of Identified Substances

4. Mass Spectrometry Images

5. Raw Data